Abstract:

 Studies on retinal mechanism of deprivation amblyopia caused by congenital cataracts recently focus on its effect on the development of central fovea and  per-papillary retinal nerve fiber layer(RNFL), as well as its electrophysiology. Previous researches suggested that form-deprivation affected the development of retinal neural circuits, including the effects on the development of ganglion cells and synaptic growth, unbalance of excitatory and inhibitory inputs in the visual afferent pathway, damage to the function of retinal cells associated with inner retina and cones of outer retina, and potential permanently affecting on retinal repair function.(Int Rev Ophthalmol, 2018, 42:   414-417)